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A review on medicinal plants used for treating ototoxicity and acoustic trauma induced hearing loss BJPS
Mahmoudian-sani,Mohammad-Reza; Sheikhshabani,SomayehHashemi; Mirfakhar,Farzaneh Sadat; Asgharzade,Samira.
Hearing loss induced by chemotherapy and acoustic trauma is mainly associated with two factors, free radical formation and apoptosis pathway activation. Despite numerous efforts on reducing the effects of these factors, no definite strategy is still determined to interfere with and control these processes. In recent studies, various protective agents, including antioxidants have been used on animal models, to inhibit the formation of free radicals thus improving hearing loss.In this review article we will discuss the role of traditional herbal medicine in treatment of noise/drug induced hearing loss, focusing on medicinal plants’ active substances,as well as their mechanisms of action in reducing or preventing the formation of free radicals thus increasing...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hearing Loss/ prevention & Control Ototoxicity Acoustic Trauma/ physiopathology Herbal Medicine/ instrumentation Oxidative stress/ drug effects Antioxidants/ therapeutic use Hearing Loss Noise-Induced/ therapy Plants Medicinal/ drug effects.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100701
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Antioxidant and cytotoxic properties of protein hydrolysates obtained from enzymatic hydrolysis of Klunzinger’s mullet (Liza klunzingeri) muscle BJPS
Rabiei,Sana; Rezaei,Masoud; Asgharzade,Samira; Nikoo,Mehdi; Rafieia-kopai,Mahmoud.
Today, consumers are looking for functional foods that promote health and prevent certain diseases in addition to provide nutritional requirements. This study aimed to evaluate the antioxidant and cytotoxic properties of Liza klunzingeri protein hydrolysates. Fish protein hydrolysates (FPHs) were prepared from L. klunzingeri muscle using enzymatic hydrolysis with papain at enzyme/substrate ratios of 1:25 and 1:50 for 45, 90 and 180 min. The antioxidant activities of the FPHs were investigated through five antioxidant assays. The cytotoxic effects on 4T1 carcinoma cell line were also evaluated. The amino acid composition and molecular weight distribution of the hydrolysate with the highest antioxidant activity were determined by HPLC. All six FPHs exhibited...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antioxidant activity; Cytotoxic effect; Protein hydrolysate; Liza klunzingeri.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100569
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